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Prescription of heroin to treatment resistant heroin addicts

BMJ 2004; 328 doi: (Published 22 January 2004) Cite this as: BMJ 2004;328:228

Double blinding is not possible

  1. Trudy Dehue (, professor of theory and history of psychology
  1. University of Groningen, 9712 TS Groningen, Netherlands

    EDITOR—As mentioned in the discussion of the paper by van den Brink et al,1 experiments with heroin maintenance cannot be double blind. This problem is much more serious than the authors acknowledge, particularly because considerable sanctions were connected to the participants' responses.

    The participants in the control groups knew …

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