Be careful when extrapolating trial data to real life

BMJ 2003; 327 doi: https://doi.org/10.1136/bmj.327.7418.812-a (Published 02 October 2003) Cite this as: BMJ 2003;327:812
  1. Nigel Dudley (nigel.dudley@leedsth.nhs.uk), consultant in elderly medicine
  1. St James's University Hospital, Leeds LS9 7TF

    EDITOR—Lenzer describes how stroke centres in the United states are under fire for their planned use of alteplase.1 Most people who have a stroke are not young but old. What both groups have in common is the difficulty in understanding even basic risk and benefit information.2

    In …

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