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Diuretics should be first line treatment for hypertension

BMJ 2003; 327 doi: https://doi.org/10.1136/bmj.327.7413.0-e (Published 28 August 2003) Cite this as: BMJ 2003;327:0-e

Question What agent is preferred as first line treatment for hypertension?

Synopsis Current evidence clearly supports using diuretics as the first line treatment for hypertension in most patients, including those with diabetes, coexisting risk factors for cardiovascular disease, and asymptomatic left ventricular hypertrophy (see the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure for exceptions). The authors combined 42 clinical trials including 192 478 patients randomised to seven major treatment …

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