Fillers POEM

Type of antidepressant is not linked to suicide rates

BMJ 2003; 327 doi: (Published 10 July 2003) Cite this as: BMJ 2003;327:0-f

Question Are suicide rates higher in depressed patients treated with tricyclic antidepressants instead of selective serotonin reuptake inhibitors?

Synopsis Many clinicians prefer prescribing selective serotonin reuptake inhibitors (SSRIs) for patients with depression to minimise the risk of suicide. By analysing the Food and Drug Administration's database of all reported adverse drug events, the authors compared completed (successful) suicide rates in patients treated with SSRIs (fluoxetine, sertraline, paroxetine, citalopram, fluvoxamine) and …

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