Prostate cancer drug may be useful for prevention

BMJ 2003; 327 doi: (Published 03 July 2003) Cite this as: BMJ 2003;327:9
  1. Janice Hopkins Tanne
  1. New York

    The American Cancer Society and the National Cancer Institute have hailed the trial of a drug for prostate cancer as a milestone for cancer prevention, although the treatment can increase the aggressiveness of the cancer in some cases. And some commentators have questioned its use as a preventive, given the trial results.

    Embedded Image

    Light micrograph of a carcinoma of the male prostate gland


    Finasteride (Proscar), which is manufactured by Merck, reduced the incidence of prostate cancer by nearly 25% in a large, randomised, controlled trial and reduced symptoms of benign prostatic hypertrophy.

    But prostate cancers that developed during the course …

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