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Obesity may confound relation of early pregnancy loss to risk of heart disease

BMJ 2003; 326 doi: (Published 22 May 2003) Cite this as: BMJ 2003;326:1146
  1. Michael J Davies, senior research fellow (
  1. Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, Adelaide, SA 5005, Australia

    EDITOR—Smith et al observe that adverse events in early life can be related to apparently disparate events later in life.1 For spontaneous pregnancy loss and subsequent ischaemic heart disease, they assume a role for inherited and acquired thrombophilias in the mother as a common aetiological factor.

    They adjusted for the potential confounding effects of maternal age at the time …

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