Thyroid function tests and hypothyroidism: Reducing concentrations further would be harmful

BMJ 2003; 326 doi: https://doi.org/10.1136/bmj.326.7398.1086-a (Published 15 May 2003) Cite this as: BMJ 2003;326:1086
  1. Mike Crilly (mike.crilly@abdn.ac.uk), senior lecturer in clinical epidemiology and public health medicine
  1. Aberdeen University Medical School, Aberdeen AB25 2ZD

    EDITOR—In their editorial on thyroid function tests and hypothyroidism, Toft and Beckett discuss the target concentration of thyroid stimulating hormone concentration for patients receiving thyroxine replacement for primary hypothyroidism.1

    They say that patients with continuing non-specific symptoms (despite a thyroid stimulating hormone concentration within the laboratory reference range) are “under-replaced.”

    They conclude that simply satisfying the recommendations of the American Thyroid Association …

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