Channelling new antidepressants to problem patients may be factor in fatal toxicity

BMJ 2003; 326 doi: https://doi.org/10.1136/bmj.326.7389.600/a (Published 15 March 2003) Cite this as: BMJ 2003;326:600
  1. Eibert R Heerdink, assistant professor (e.r.heerdink@pharm.uu.nl),
  2. Gerard W K Hugenholtz, hospital pharmacist,
  3. Welmoed E E Meijer, manager, clinical monitoring,
  4. Antoine C G Egberts, professor of pharmacoepidemiology
  1. Department of Pharmacoepidemiology, Utrecht University, PO Box 80082, NL-3508 TB Utrecht, Netherlands
  2. Altrecht Institute for Mental Health Care, Dolderseweg 174, 3734 BN Den Dolder, Netherlands
  3. Kendle International, Bolognalaan 40, 3584 CJ Utrecht
  4. Department Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, PO Box 80082, 3508 TB Utrecht

    EDITOR—Buckley and McManus provide a good overview of all reported deaths in the United Kingdom that were suspected to be due to overdosing with antidepressants over the past 15 years compared with prescription rates of the individual drugs.1 However, we seriously doubt the validity of their conclusions.

    Buckley …

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