Watchfulness may not be as good as surgery for prostate cancer

BMJ 2002; 325 doi: https://doi.org/10.1136/bmj.325.7377.1423 (Published 14 December 2002) Cite this as: BMJ 2002;325:1423
  1. Paul B Silcocks, public health physician (pbs@shatton29.freeserve.co.uk)
  1. Trent Cancer Registry, Weston Park Hospital, Sheffield S10 2SJ

EDITOR—Gottlieb's news story that watchful waiting is as good as surgery in prostate cancer raises three issues.1

Firstly, the conclusion would be possible only if the study had been specifically designed as a non-inferiority or equivalence trial and the resulting confidence limits lay within a prespecified and widely accepted interval.

Secondly, …

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