Antibiotic prophylaxis after CSF leaks lacks evidence base

BMJ 2002; 325 doi: https://doi.org/10.1136/bmj.325.7371.1037/a (Published 02 November 2002) Cite this as: BMJ 2002;325:1037
  1. James R Greig, consultant microbiologist (jjrgreig@yahoo.co.uk)
  1. Derriford Hospital, Plymouth, Devon PL6 8DH

    EDITOR—Santarius et al in their Minerva article perpetuate the unconfirmed and potentially harmful myth that leaks of cerebrospinal fluid should be treated with antibiotic prophylaxis.1 This lacks an evidence base, and there argge sound practical reasons why this practice will not be effective.

    This issue was …

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