Fish, meat, and risk of dementia: cohort study
BMJ 2002; 325 doi: https://doi.org/10.1136/bmj.325.7370.932 (Published 26 October 2002) Cite this as: BMJ 2002;325:932- Pascale Barberger-Gateau, senior lecturer (Pascale.Barberger-Gateau@isped.u-bordeaux2.fr),
- Luc Letenneur, researcher,
- Valérie Deschamps, research fellow,
- Karine Pérès, esearch fellow,
- Jean-François Dartigues, professor,
- Serge Renaud, researcher.
- INSERM U330, Université Victor Segalen Bordeaux 2, case n£11, 146 rue Léo-Saignat, 33076 Bordeaux Cedex, France
- Correspondence to: P Barberger-Gateau
- Accepted 7 May 2002
Participants, methods, and results
We obtained data from the PAQUID (Personnes Agées QUID) epidemiological study of cognitive and functional ageing (www.healthandage.net/html/min/paquid/entrance.htm). During the third wave of the study (1991-2) investigators visited 1674 people aged 68 and over without dementia and living at home in 75 parishes in southwestern France and recorded their frequency of consumption of meat and fish or seafood: daily, at least once a week (but not every day), from time to time (but not every week), never. Participants were followed up two, five, and seven years afterwards: 1416 (84.6 %) had at least one follow up visit. All the participants who had lost three points or more on the mini-mental state examination since a previous visit or were suspected of having dementia according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, third edition, revised (DSM-III-R) were visited by a neurologist to confirm the diagnosis.
We …