Hormone trial for disease prevention stopped early

BMJ 2002; 325 doi: (Published 13 July 2002) Cite this as: BMJ 2002;325:61
  1. Janice Hopkins Tanne
  1. New York

    A US randomised, placebo controlled, double blind trial to evaluate oestrogen and progestogen in postmenopausal women was stopped early by the Women's Health Initiative because health risks exceeded health benefits by a small margin.

    It is the first trial to examine whether continuous oestrogen plus progestogen has a favourable or unfavourable effect on coronary heart disease and overall risks and benefits in healthy women.

    JAMA has already posted the article on its website ( The article will then be …

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