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Antioxidant vitamins make lipid lowering drugs less effective

BMJ 2001; 323 doi: (Published 08 December 2001) Cite this as: BMJ 2001;323:1323
  1. Scott Gottlieb
  1. New York

    The combination of simvastatin and niacin can reduce the risk factors associated with myocardial infarction by 60-90% in patients at high risk of a major cardiac event, researchers at the University of Washington in Seattle have found.

    Furthermore, this same patient population should be advised to stop taking antioxidant vitamins. “Physicians should question their patients and have them stop using antioxidant vitamins. It is the opposite of what I used to say,” the study's lead author, Dr B Greg Brown of the University of Washington commented.

    The recommendations emanate from new research, which found that a combination of antioxidant …

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