NSAIDs can lower risk of Alzheimer's

BMJ 2001; 323 doi: (Published 01 December 2001) Cite this as: BMJ 2001;323:1269
  1. Scott Gottlieb
  1. New York

    Long term use of anti-inflammatory drugs such as ibuprofen and naproxen can lower the risk of Alzheimer's disease, a new study has said.

    Studies done in the laboratory and animal models had previously suggested that anti-inflammatory drugs prevented Alzheimer's disease or delayed its onset. Researchers have theorised that the drugs work by reducing inflammation in the brain. To date, this is the first such study in people to show a positive effect.

    The researchers, led by Dr Bruno Stricker of the Erasmus Medical Center in Rotterdam, found that adults who used non-steroidal anti-inflammatory drugs for at least two years were 80% less likely to develop Alzheimer's disease than individuals who …

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