HIV-1 drug resistance in primary infections in the UK

BMJ 2001; 323 doi: https://doi.org/10.1136/bmj.323.7313.632b (Published 15 September 2001) Cite this as: BMJ 2001;323:632
  1. Sarah Fidler, lecturer in HIV (s.fidler@ic.ac.uk),
  2. John Frater, Medical Research Council research fellow,
  3. John Clarke, research scientist,
  4. Jonathan Weber, Jefferiss professor of communicable diseases
  1. Department of HIV/Genitourinary Medicine, Jefferiss Trust Laboratories, Wright-Fleming Institute, Imperial College School of Medicine, St Mary's Hospital, London W2 1PG

    EDITOR—The UK Collaborative Group on Monitoring the Transmission of HIV Drug Resistance reports an estimated prevalence of transmitted HIV drug resistance in 2000 of 27%.1

    In an ongoing study of acute primary HIV infection at St Mary's Hospital, London, England, we have identified 28 seroconverters since January 2000. All patients sequenced to date (15/28) have no evidence of drug resistant mutations in either reverse transcriptase or protease before …

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