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Moderate use of painkillers presents no harm to kidneys

BMJ 2001; 323 doi: (Published 28 July 2001) Cite this as: BMJ 2001;323:184
  1. Deborah Josefson
  1. San Francisco

    A new study counters the belief that moderate, chronic use of common analgesics results in kidney damage (JAMA 2001;286:315-21).

    The study investigated moderate, chronic intake of analgesics—equivalent to three or four tablets a week. It was conducted by researchers from Brigham and Women's Hospital in Boston and was funded by the National Institutes of Health and by MacNeil Consumer Products, the maker of Tylenol, a popular brand of paracetamol.

    Kathryn Rexrode, Julie Buring, and colleagues compared analgesic intake and renal function in a cohort of 11 032 initially healthy men, ranging in age from 40 to 84, who were enrolled in the physicians' health study. This study lasted 14 years, from September …

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