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Relationship between smoking and wrinkles clarified

BMJ 2001; 322 doi: https://doi.org/10.1136/sbmj.0105136b (Published 01 May 2001) Cite this as: BMJ 2001;322:0105136b
  1. James S Dawson1
  1. 1Leicester

The fact that people who smoke develop wrinkles at an earlier age than their non-smoking counterparts seems to be due to an imbalance of extracellular matrix degrading enzymes and their respective inhibiting factors, according to an article in the Lancet (2001;357:935–6).

Researchers investigating the role of ultraviolet light on the expression of matrix metalloproteinase (MMP) enzymes in buttock skin of healthy volunteers incidentally found that this enzyme was already being …

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