Gene test could help detect colorectal cancerBMJ 2001; 322 doi: https://doi.org/10.1136/bmj.322.7300.1445/a (Published 16 June 2001) Cite this as: BMJ 2001;322:1445
- Scott Gottlieb
- New York
DNA from colorectal cancer cells that have been shed can be isolated from faeces and tested for the presence of most colorectal cancers using three genetic mutations associated with tumours, a new study says.
Dr Jin Jen, from the National Institutes of Health in Bethesda, Maryland, and colleagues, developed a method of purifying DNA from stool samples and then compared paired DNA samples from stools and tumours from 51 patients with colorectal cancer. They looked specifically for three gene mutations commonly found in colorectal cancer: TP53, BAT26, and K-RAS (Journal of the National …