Intended for healthcare professionals


Existence and quality of written antenatal screening policies in the United Kingdom: postal survey

BMJ 2001; 322 doi: (Published 06 January 2001) Cite this as: BMJ 2001;322:22
  1. Beverley Lane, research nurse,
  2. Kirsty Challen (kirstychallen{at}, research assistant,
  3. Hilary J Harris, research associate,
  4. Rodney Harris, emeritus professor (medical genetics)
  1. Genetic Enquiry Centre, St Mary's Hospital, Manchester M13 0JH
  1. Correspondence to: K Challen
  • Accepted 1 August 2000

The assessment of antenatal care of women at increased risk of having a baby with Down's syndrome, neural tube defect, thalassaemia, and cystic fibrosis that was undertaken by the national confidential inquiry into counselling by non-geneticists revealed several problems, including poor record keeping.1 These problems were reported to the Department of Health in five specific papers and four summary, peer reviewed papers and on the internet.2 The Royal College of Obstetricians and Gynaecologists then issued guidelines recommending that antenatal units have written policies for screening for Down's syndrome and for neural tube defect and that haemoglobinopathy screening be offered to all patients whose ethnic origin makes them susceptible.3 There is less consensus on screening for cystic fibrosis (UK National Screening Committee, joint meeting of the antenatal and child health screening subgroups, cystic fibrosis workshop, London, 2 June 1999). We assessed the response among antenatal staff to the outcomes of the national confidential inquiry.

Methods and results

In 1999 directors of obstetrics and midwifery throughout the United Kingdom were asked to complete an anonymous questionnaire concerning their awareness of the national confidential inquiry and its effects on practice. (Copies of the questionnaires are available on the BMJ's website.) Midwives were also asked to submit their unit's written policies, which we assessed using the royal college's criteria (table).3

Adherence of midwifery units' written policies to Royal College of Obstetricians and Gynaecologists' guidelines on screening*

View this table:

A total of 242 obstetricians were sent questionnaires, 181 (75%) of whom responded. Of these, 29 (16%) were aware of the inquiry (four having supplied information to it), 13 (7%) were aware of the specific recommendations for Down's syndrome, 7 (4%) those for neural tube defects, and 6 (3%) those for cystic fibrosis. Four obstetricians stated that they had implemented recommendations, and one was auditing their effect on practice. Of the 273 midwives who were sent questionnaires, 160 (59%) responded; 33 (21%) were aware of the inquiry, 27 (18%) were familiar with the recommendations for Down's syndrome, 13 (9%) those for neural tube defects, and 9 (6%) those for cystic fibrosis. The figures for obstetricians and those for midwives are not evidently related.

Thirty nine units (24%) lacked local and regional policies for Down's syndrome, 55 (34%) for neural tube defect, 104 (65%) for haemoglobinopathy, and 125 (78%) for cystic fibrosis; 55 units updated their policies annually, 36 “[when] required”, one every five years, and one every three months. Neither awareness of the inquiry nor whether a coordinator was responsible for screening had an effect on the updating of policies. In 108 units (90%) policies were said to be agreed by everyone implementing them. One unit reported that community midwives were excluded from agreement of policy, another that medical staff constructed policies without consulting midwives. Written policies were received from 65 midwifery units; the adherence of these policies to the royal college guidelines is shown in the table.

A key person responsible for coordinating screening was reported in 106 units (68%). This correlated with the existence of a local policy for Down's syndrome (P=0.045) but not for neural tube defect or haemoglobinopathy. Of these people 42 were midwifery managers, 23 specialist coordinators (including one genetic counsellor), and 18 consultants.

Where written policies existed they varied widely in adherence to the guidelines, and only one covered all five points. There was no evidence that obstetricians' and midwives' awareness of the inquiry (the evidence base for many policies) was consistent within units. Community midwives were sometimes excluded from policymaking, even though they were relied on for identification and initial counselling of women. One policy “agreed by all” had criteria for screening and referral that differed for each named consultant.


We found that antenatal units were generally unaware of the royal college's recommendations on screening. National guidelines and local written policies should be adopted to promote informed choice and equity of service.1 Coordinated antenatal genetic screening will be even more important with the mapping of the human genome. Units without an identified person responsible for antenatal screening face the risk of being overwhelmed by advances in the field, and national audits will be compromised if no single person can be approached for reliable information.


Contributors: BL conceived the study and distributed questionnaires. BL and KC collated and analysed data. HJH contributed to interpretation and analysis of data. The paper was written jointly by all authors. RH is the guarantor for the study.


  • Competing interests None declared.

  • Funding Department of Health's confidential inquiry into genetic counselling by non-geneticists.

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    Copies of the questionnaires are available on the BMJ's website


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