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Studies in meta-analysis of treatment of stable angina had methodological flaws

BMJ 2000; 321 doi: (Published 02 December 2000) Cite this as: BMJ 2000;321:1408
  1. S C Eccleshall (, interventional cardiology fellow,
  2. G J Laarman, consultant cardiologist,
  3. J Nolan, consultant cardiologist
  1. OLVG Hospital, postbus 95500, 1090 HM Amsterdam, Netherlands
  2. North Staffordshire Hospital, Stoke on Trent ST4 6QG

    EDITOR—Bucher et al's meta-analysis of the treatment of stable angina with percutaneous transluminal coronary angioplasty or medical treatment is based on a small number of trials with methodological flaws. 1 2 The conclusions could have considerable adverse effects on the provision of revascularisation services, and we wish to draw attention to problems with the meta-analysis. Its results should not be used to guide clinical practice or decision making in public health.

    Sievers et al recruited asymptomatic patients to randomisation between angioplasty and medical …

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