Intended for healthcare professionals


Phenylpropanolamine in drugs could be a risk for stroke

BMJ 2000; 321 doi: (Published 28 October 2000) Cite this as: BMJ 2000;321:1037
  1. Fred Charatan
  1. Florida

    A five year study by Yale University, Connecticut, has found a small, but significant risk of haemorrhagic stroke in women taking non-prescription cough and cold medicines, appetite suppressants, and some prescription decongestants containing phenylpropanolamine (PPA).

    After hearing the evidence presented by the researchers—who were headed by Dr Walter Kernan, an associate professor of medicine at Yale—an advisory 14 member panel of the US Food and Drug Administration (FDA) voted overwhelmingly to ban …

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