Intended for healthcare professionals


Gene therapy can reduce tumours

BMJ 2000; 321 doi: (Published 12 August 2000) Cite this as: BMJ 2000;321:400
  1. Scott Gottlieb
  1. New York

    A new trial involving patients with recurrent head and neck cancer found that those who received gene therapy plus chemotherapy had more tumour regression than those receiving chemotherapy alone. The gene therapy group also experienced no tumour progression within six months of therapy, the study found.

    The study involved 30 patients with head and neck cancer, most of whom had already had surgery or radiation but who suffered a recurrence. Patients in whom this kind of cancer recurs are considered to be incurable. In the study, researchers used a virus known as Onyx-015 to deliver therapeutic genes to sites …

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