Scientists grow artificial thymus cells
BMJ 2000; 321 doi: https://doi.org/10.1136/bmj.321.7254.136/f (Published 15 July 2000) Cite this as: BMJ 2000;321:136- Abi Berger
- BMJ
Engineers have designed a three dimensional grid that allows stem cells to differentiate into mature T cells ex vivo. The resulting cells are genetically similar to native thymus cells, are fully functional, and may lead to the production of T cells whose reactivity can be directed towards specific foreign antigens, potentially replacing parts of the immune system damaged by disease or chemotherapy (Nature Biotechnology 2000;18:729-34).
The grid, used by Dr David Scadden, director of experimental haematology, and …
Log in
Log in using your username and password
Log in through your institution
Subscribe from £164 *
Subscribe and get access to all BMJ articles, and much more.
* For online subscription
Access this article for 1 day for:
£30 / $37 / €33 (excludes VAT)
You can download a PDF version for your personal record.