Intended for healthcare professionals

News Extra [these Stories Appear Only On The Web]

Scientists grow artificial thymus cells

BMJ 2000; 321 doi: (Published 15 July 2000) Cite this as: BMJ 2000;321:136
  1. Abi Berger
  1. BMJ

    Engineers have designed a three dimensional grid that allows stem cells to differentiate into mature T cells ex vivo. The resulting cells are genetically similar to native thymus cells, are fully functional, and may lead to the production of T cells whose reactivity can be directed towards specific foreign antigens, potentially replacing parts of the immune system damaged by disease or chemotherapy (Nature Biotechnology 2000;18:729-34).

    The grid, used by Dr David Scadden, director of experimental haematology, and …

    View Full Text

    Log in

    Log in through your institution


    * For online subscription