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Cochlear hair cells generated in mammals after birth

BMJ 2000; 320 doi: (Published 20 May 2000) Cite this as: BMJ 2000;320:1360
  1. Abi Berger
  1. BMJ

    Hair cells from the inner ear can now be replaced by using gene transfer techniques. Scientists in California have succeeded in generating new hair cells in the cochlea and vestibular apparatus of the inner ear of rats.

    They believe that this is an important step towards potential hair cell regeneration in adult mammals and could provide a biological alternative to cochlear implants to restore hearing loss (Nature Neuroscience 2000;3;580-6).

    Dr Wei-Qiang Gao, a developmental neurobiologist, and Lisa Zheng at the biotechnology company Genentech, have been working on …

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