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Study throws doubt on protective effects of HRT for heart disease

BMJ 2000; 320 doi: (Published 25 March 2000) Cite this as: BMJ 2000;320:826
  1. Scott Gottlieb
  1. New York

    The effectiveness of hormone replacement therapy in treating heart disease in postmenopausal women remained in question as contradictory studies were presented at a major cardiology conference in California.

    Researchers from Wake Forrest University Baptist Medical Center in North Carolina presented findings at the American College of Cardiology's 49th annual scientific sessions in Anaheim, California, showing that neither oestrogen alone nor oestrogen combined with progestogen slowed the advances of heart disease in postmenopausal women or significantly lowered cholesterol concentrations.

    Known as the ERA study (the estrogen replacement and arteriosclerosis trial), …

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