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Coeliac disease specific antigen found

BMJ 2000; 320 doi: (Published 18 March 2000) Cite this as: BMJ 2000;320:736
  1. Abi Berger
  1. BMJ

    The discovery of a coeliac disease specific antigen could offer a new route for treatment of the condition. Dr Robert Anderson and his colleagues at the Institute of Molecular Medicine in Oxford have identified a peptide in wheat that elicits a specific immune response in people with coeliac disease.

    If this immune response could be blocked, then the need to stick to a gluten free diet could become obsolete (Nature Medicine 2000;6:337-42).

    Dr Anderson, a gastroenterologist, and his team set out to find the toxic part of the gluten molecule. It is already known that gluten can be separated into …

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