Coeliac disease specific antigen foundBMJ 2000; 320 doi: https://doi.org/10.1136/bmj.320.7237.736/b (Published 18 March 2000) Cite this as: BMJ 2000;320:736
- Abi Berger
The discovery of a coeliac disease specific antigen could offer a new route for treatment of the condition. Dr Robert Anderson and his colleagues at the Institute of Molecular Medicine in Oxford have identified a peptide in wheat that elicits a specific immune response in people with coeliac disease.
If this immune response could be blocked, then the need to stick to a gluten free diet could become obsolete (Nature Medicine 2000;6:337-42).
Dr Anderson, a gastroenterologist, and his team set out to find the toxic part of the gluten molecule. It is already known that gluten can be separated into …