Textbook of Prostate Cancer: Pathology, Diagnosis and Treatment
BMJ 2000; 320 doi: https://doi.org/10.1136/bmj.320.7228.192/a (Published 15 January 2000) Cite this as: BMJ 2000;320:192
This article has a correction. Please see:
- Neville W Harrison, consultant urological surgeon
- Brighton
Eds Amir V Kaisary, Gerald P Murphy, Louis Denis, Keith Griffiths
Martin Dunitz, £75, pp 384
ISBN 1 85317 422 X
Rating: 
The demonstration by Huggins and colleagues in 1941 of the effects of castration on prostate cancer was a breakthrough that won a Nobel prize and generated great optimism that cancer could be cured. As evidence gradually accumulated there was a reluctant realisation that hormone manipulation, despite its sometimes dramatic effects, is only a palliative treatment; there were to be few substantial advances in the management of prostate cancer …
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