Intended for healthcare professionals


Clinical review overstates genetic case for schizophrenia

BMJ 1999; 319 doi: (Published 04 December 1999) Cite this as: BMJ 1999;319:1498
  1. Joanna Moncrieff, specialist registrar in psychiatry (
  1. Department of Psychological Medicine, Chelsea and Westminster Hospital, London SW10 9NH

    EDITOR—McGuffin and Martin overstate the case for the genetic basis of psychiatric and behavioural disorders and are overoptimistic about the potential benefits of DNA testing.1 For example, in common with other proponents of the genetic theory of schizophrenia, they quote the most strongly positive studies, ignoring negative ones and ones that show weaker effects. …

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