Intended for healthcare professionals


Reducing vertical transmission of HIV in the UK

BMJ 1999; 319 doi: (Published 06 November 1999) Cite this as: BMJ 1999;319:1211

At last the UK is getting serious about reducing mother to child transmission

  1. Angus Nicoll, consultant epidemiologist,
  2. Catherine Peckham, professor
  1. HIV and STD Division, PHLS Communicable Disease Surveillance Centre, London NW9 5EQ
  2. Department of Epidemiology and Public Health, Institute of Child Health, London WC1N 1EH

    Papers pp 1227, 1230

    For five years we have known that administering zidovudine to HIV infected women during pregnancy and in labour, and to the neonate for the first 6 weeks of life, greatly reduces mother to child transmission of HIV.1 This intervention, together with delivery by caesarean section and avoiding breast feeding, has reduced the risk of transmission from over 20% to well under 5%.2 In the United States, where antiretroviral therapy is widely used to reduce perinatal transmission, the incidence of AIDS in infants, a sensitive indicator of mother to child transmission, has fallen by 80%.3 In the United Kingdom, although routine antenatal testing for HIV infection has officially been recommended for high prevalence areas since 1994, most maternal HIV infections remain undetected.4 Thus the number of infants presenting with AIDS in the UK has not declined, as it has in other European countries, and in 1997 was higher than in France, Italy, or Spain. Yet these countries have adult HIV burdens four or more times greater than that of the UK.5

    In 1997 the unlinked anonymous programmes of HIV testing found evidence of 265 births to HIV infected women, 195 …

    View Full Text

    Log in

    Log in through your institution


    * For online subscription