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COX 2 inhibitors might be useful in cancer prevention

BMJ 1999; 319 doi: (Published 30 October 1999) Cite this as: BMJ 1999;319:1155
  1. Scott Gottlieb
  1. New York

    Scientists have discovered that patients with familial adenomatous polyposis (a condition associated with a 100% lifetime risk of colon cancer) who underwent six months of treatment with the COX 2 inhibitor celecoxib, had a 28% reduction in the number of adenomatous polyps.

    The lead author, Dr Gideon Steinbach, associate internist at MD Anderson Cancer Center in Houston, presented the findings at the American College of Gastroenterology's 64th annual scientific meeting in Phoenix. He said that the study of 77 patients with familial adenomatous polyposis …

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