Scientists identify enzymes implicated in Alzheimer's

A team of scientists working at Amgen, a leading biotechnology company at Thousand Oaks, California, has succeeded in identifying two proteases believed to be responsible for the formation of amyloid plaques in the brains of patients with Alzheimer's disease.

Their report is published in the current issue of Science (1999;286:735-41) Amyloid has been clearly implicated in the pathogenesis of Alzheimer' sdisease (BMJ 1998;317:102). The Amgen team found that the deposition …