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Scientific foundation of mammographic screening is based on inconclusive research in Sweden

BMJ 1999; 319 doi: (Published 03 July 1999) Cite this as: BMJ 1999;319:55
  1. Göran Sjönell, Family physician (,
  2. Lars Ståhle, Assistant professor
  1. Kvartersakuten Matteus, Surbrunnsgatan, 66 SE 11327 Stockholm, Sweden
  2. Department of Clinical Pharmacology, Karolinska Institute, Huddinge University Hospital, SE-14186 Huddinge, Sweden

    EDITOR—In a letter Rosén and Rehnqvist criticised our analysis of mammographic screening in Sweden.1 We respond here to their criticism. The Swedish Board of Health and Welfare claims that mammographic screening has been shown to be effective in Swedish high quality clinical trials. A re-evaluation of these trials casts serious doubt on that conclusion.

    A meta-analysis of five Swedish clinical trials showed a significant 24% reduction in mortality from breast cancer, but the control groups in four of the …

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