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Adjusting for multiple testing in studies is less important than other concerns

BMJ 1999; 318 doi: (Published 08 May 1999) Cite this as: BMJ 1999;318:1288
  1. Thomas V Perneger, Medical epidemiologist (
  1. Institute of Social and Preventive Medicine, University of Geneva, CMU, CH-1211 Geneva 4, Switzerland

    EDITOR—In a paper in the American Journal of Public Health Aickin stated that “there is substantial debate… concerning when (if ever) adjustment for multiple testing is warranted.”1 I am glad that he has joined the debate in the BMJ over Bonferroni adjustments but find his arguments unconvincing.2 Yes, “researchers who adjust P values almost always present them for their individual hypotheses,” as he says. This is why they should not worry about unrelated tests and renounce a statistical technique that focuses …

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