Intended for healthcare professionals


Practical problems in recruiting patients with schizophrenia into randomised controlled trials

BMJ 1999; 318 doi: (Published 17 April 1999) Cite this as: BMJ 1999;318:1075
  1. Helen Lester, Sheldon research fellow (,
  2. Sue Wilson, Research fellow
  1. Department of General Practice, University of Birmingham Medical School, Birmingham B15 2TT

    EDITOR—Thornley and Adams surveyed the content and quality of trials relating to the care of those with schizophrenia.1 They found that studies were of short duration (only 19% with six months of follow up), had few patients (mean number 65), and rarely community based (19%). They concluded that “large studies, of long duration … are needed,” but they did not discuss the possible reasons for these findings.

    We are currently undertaking a community based randomised controlled …

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