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Reflux “increases risk of adenocarcinoma of oesophagus”

BMJ 1999; 318 doi: https://doi.org/10.1136/bmj.318.7187.827 (Published 27 March 1999) Cite this as: BMJ 1999;318:827
  1. Scott Gottlieb
  1. New York

    Chronic heartburn can greatly increase a person's risk of developing adenocarcinoma of the oesophagus, according to a new study that adds strong epidemiological support to a widely held assumption.

    The study, published in the New England Journal of Medicine (1999;340:825-31), found that the risk of oesophageal adenocarcinoma was almost eight times higher among people in whom heartburn, regurgitation, or both occurred at least once a week than among people without these …

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