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Trends in deaths from malignant neoplasia of liver are poor indicator of hepatitis C infection

BMJ 1999; 318 doi: (Published 20 March 1999) Cite this as: BMJ 1999;318:808
  1. Helen E Harris (, Research associate.,
  2. Mary E Ramsay, Consultant epidemiologist.,
  3. Koye Balogun, Clinical scientist.,
  4. Graeme J M Alexander, Consultant hepatologist.
  1. Immunisation Division, Communicable Disease Surveillance Centre, Public Health Laboratory Service, London NW9 5EQ
  2. Department of Medicine, Addenbrooke's Hospital, Cambridge CB2 2QQ

    EDITOR—Taylor Robinson et al have suggested that increasing mortality from liver cancer in the United Kingdom may be the result of cirrhosis induced by hepatitis C virus.1 However, the increase they report is in deaths from malignant neoplasia of the liver (hepatocellular carcinomas, cancers of the intrahepatic bile ducts, and liver cancers that are not specified as either primary or secondary2). The number of deaths due to hepatocellular carcinoma (which is aetiologically linked to hepatitis C) has been fairly stable between 1990 and 1995 (table).

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    Trends in …

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