New HIV strain may be resistant to drugs
BMJ 1998; 317 doi: https://doi.org/10.1136/bmj.317.7151.100a (Published 11 July 1998) Cite this as: BMJ 1998;317:100- Scott Gottlieb, Clegg scholar
- BMJ
The best available antiretroviral drugs, including protease inhibitors, may lose their potency against HIV because new strains of the virus resistant to the strongest drugs have already emerged.
A team of AIDS researchers has reported a case in which a person has become infected with a strain of HIV that is resistant to six of the 11 approved antiretroviral drugs for HIV, including protease inhibitors. Protease inhibitors have been approved for two years; used as part of triple combination therapies, they have contributed to a dramatic decline in death rates from AIDS. Protease inhibitors work by blocking the construction of proteins considered pivotal to replication of …
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