Effect of calcium supplementation during pregnancy on blood pressure of offspring

BMJ 1998; 316 doi: https://doi.org/10.1136/bmj.316.7126.234 (Published 17 January 1998) Cite this as: BMJ 1998;316:234

Authors cannot be sure of effect's generalisability to all children aged 5-9

  1. Imogen F D Stephens, Senior registrar in public health medicinea
  1. aArgyll and Clyde Health Board, Paisley PA2 7BN
  2. bSpecial Programme of Research, Development and Research Training in Human Reproduction, World Health Organisation, 1211 Geneva 27, Switzerland
  3. cCentro Latinamericano de Perinatologia, Pan-American Health Office/World Health Organisation, Montevideo, Uruguay

    Editor-Béliz¡n et al claim to have shown, in a double blind randomised controlled trial, that the systolic blood pressure of children between the ages of 5 and 9 years was lower in those whose mothers had taken calcium during their pregnancy than in those whose mothers had taken placebo.1 Such a finding has epidemiological and public health importance since it may provide the first grade A evidence that intrauterine programming of childhood blood pressure both exists and can be modified by simple nutritional intervention.

    While the authors admit that this effect …

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