Study linking enteroviral infection with motor neurone disease is not confirmed

BMJ 1997; 315 doi: https://doi.org/10.1136/bmj.315.7119.1380 (Published 22 November 1997) Cite this as: BMJ 1997;315:1380
  1. Scott Rice, Research officera,
  2. Roger Pamphlett, Senior lecturera
  1. a Department of Pathology D06, University of Sydney, Sydney, New South Wales 2006, Australia

    Editor—A viral cause of sporadic motor neurone disease has long been suspected because poliomyelitis affects motor neurones selectively. Much interest was generated by a report by Woodall et al that enteroviral sequences were found more frequently in tissue from patients with motor neurone disease than in control nervous tissue.1 We wanted to see if we could confirm this finding.

    We studied paraffin sections …

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