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Caloric restriction may retard cancers

BMJ 1997; 315 doi: https://doi.org/10.1136/bmj.315.7119.1327l (Published 22 November 1997) Cite this as: BMJ 1997;315:1327
  1. Debbie Josefson
  1. San Francisco

    Scientists at the United States National Institute of Health's Institute of Environmental Health Sciences have uncovered a mechanism by which restricting calorie intake could retard the development and progression of cancers. The work, which was led by Dr Sandra Dunn and Dr Frank Kari, is reported in Cancer Research (1997;57:4667-72).

    Dietary factors contribute to an estimated 33% of deaths from cancer in the West. Furthermore, a wasting syndrome is a prominent feature of many cancers and chronic illnesses, and …

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