Adding heat probe treatment to adrenaline injection for spurting haemorrhage of peptic ulcersBMJ 1997; 315 doi: https://doi.org/10.1136/bmj.315.7114.1016 (Published 18 October 1997) Cite this as: BMJ 1997;315:1016
Injection of adrenaline and human thrombin is best option
- S H Hussaini, Lecturer in medicinea,
- MA Hull, Lecturer in medicinea
- a Division of Medicine, St James's University Hospital, Leeds LS9 7TF
- b Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
Editor—Chung et al reported a randomised study examining the efficacy of giving heat probe treatment after endoscopic adrenaline injection for actively bleeding peptic ulcers.1 No benefit over adrenaline injection alone was detected. However, a subgroup analysis of patients with spurting haemorrhage showed benefit (reduced surgical rates) in the group given dual treatment. We are concerned about the stratification of patients in this subgroup analysis.
Endoscopic treatment is more likely to fail in patients with posterior duodenal ulcers than in patients with anterior ulcers. …