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Data on results of using different antiepileptic drugs do exist

BMJ 1997; 315 doi: (Published 04 October 1997) Cite this as: BMJ 1997;315:885
  1. Martin J Brodie, Directora
  1. Epilepsy Unit, University Department of Medicine and Therapeutics, Western Infirmary, Glasgow G11 6NT

    Editor—Anthony Marson and colleagues have challenged me to produce “hard empirical evidence” in support of a mechanistic hypothesis in the management of epilepsy.1 The best data come from a recently presented, as yet unpublished, double blind substitution study.2 In this, 7% of 215 patients reporting a median of five partial seizures a month when taking monotherapy with …

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