Screening for mannose binding protein gene in routine practice is unnecessary

BMJ 1997; 315 doi: https://doi.org/10.1136/bmj.315.7105.428 (Published 16 August 1997) Cite this as: BMJ 1997;315:428
  1. Catherine Hawke, Senior registrar in public health medicinea
  1. a Directorate of Public Health and Health Policy, Oxfordshire Health Authority, Oxford OX3 9LG

    Editor—John A Summerfield and colleagues suggest that mutations in the mannose binding protein gene are associated with infections in children attending their hospital paediatric department.1 They also conclude that screening for such mutations should be included in the investigation of severe or frequent infections, but they fail to explain why. What is the point of screening? How can identifying such mutations in these children improve …

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