Criticism of prophylaxis of gastrointestinal bleeding with H2 receptor antagonists is wrong

BMJ 1997; 315 doi: https://doi.org/10.1136/bmj.315.7104.371 (Published 09 August 1997) Cite this as: BMJ 1997;315:371
  1. T M Cook, Specialist registrar in anaesthesiaa
  1. a Bristol Royal Infirmary, Bristol BS2 8HW

    Editor—The short report by D L A Wyncoll and colleagues is provocatively titled “H2 blockers in the intensive care unit: ignoring the evidence?”1 The authors state that a recent meta-analysis by Cook et al has “shown that sucralfate is associated with a lower incidence of pneumonia and mortality than H2 receptor antagonists.”2 They infer that patients referred to their unit who continue to receive H2 receptor antagonists are receiving suboptimal treatment.

    The paper by Cook et al sought to resolve the results of previous …

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