Funding is important for randomised trials of surgery

BMJ 1997; 315 doi: https://doi.org/10.1136/bmj.315.7103.310 (Published 02 August 1997) Cite this as: BMJ 1997;315:310
  1. Stephen Bridgman, Senior lecturer in public health and epidemiologya,
  2. James Elder, Professor of surgerya,
  3. Richard Gray, Director, West Midlands Clinical Trials Unitb,
  4. Richard Lilford, NHS clinical trials adviserb
  1. a University of Keele, School of Postgraduate Medicine, Stoke on Trent ST4 7NY
  2. b University of Birmingham, Birmingham

    Editor—In their editorial on removing bias in surgical trials A G Johnson and J Michael Dixon mention the safety and efficacy register of new interventional procedures.1 We consider this register to be an encouraging start, but it is not a substitute for randomised controlled trials of new surgical techniques.

    The opportunity to participate in randomised controlled trials should be offered to all suitable patients because randomisation minimises bias and moderate bias may obscure or exaggerate moderate differences between treatments.2 Some …

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