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Trials of streptokinase in stroke depend on early, accurate diagnosis

BMJ 1997; 315 doi: (Published 19 July 1997) Cite this as: BMJ 1997;315:187
  1. Keith W Muir, Registrara
  1. a Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Glasgow G51 4TF

    Editor—Paul Dorman and Peter Sandercock's survey of access to computed tomography provides scant reassurance to those with experience of trials of streptokinase in acute stroke.1 Randomised controlled trials (involving over 1200 patients) have provided ample evidence of the hazard of streptokinase in stroke. The availability of computed tomography is only a minor factor in the safe conduct of further trials. Despite computed tomography being carried out before treatment, intracerebral haemorrhage …

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