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Major journals should peer review trials at protocol stage

BMJ 1997; 314 doi: (Published 07 June 1997) Cite this as: BMJ 1997;314:1691
  1. Alexander Foss, Consultant ophthalmologista,
  2. Mark Westcott, Research fellowb
  1. a Queens Medical Centre, Nottingham NG7 2UH
  2. b Institute of Ophthalmology, London EC1V 9EL

    Editor—Increasing concern over the poor quality of medical research, and particularly over the conduct of clinical trials, has been voiced by the editors of the major medical journals. This unease has taken expression in the form of the CONSORT statement,1 2 which states the criteria by which a trial should be judged. Unfortunately, most trials are not vigorously assessed until their results are submitted to a journal for publication–a time when it is too late for any errors in trial design to be remedied. There is also the second major problem of negative …

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