Medicine And Books

Multiple Sclerosis (Clinical and Pathogenetic Basis)

BMJ 1997; 314 doi: (Published 26 April 1997) Cite this as: BMJ 1997;314:1288
  1. P K Newman, consultant neurologist
  1. Middlesbrough General Hospital, Middlesbrough

    Ed C S Raine, H F McFarland, W W Tourtellotte / Chapman and Hall, £125, pp 426 / ISBN 412 308908

    Multiple sclerosis is one of the more common and most feared neurological diseases of young adults, with at least 50 000 cases in the United Kingdom and more than a million worldwide. Predominantly T cell mediated autoimmune mechanisms, triggered by earlier virus infection or other factors in those who are genetically predisposed, lead to destruction of myelin in the brain, optic nerves, and spinal cord. Research has yet to fully unravel the elusive pathogenesis or provide an effective …

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