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Authors' reply

BMJ 1996; 313 doi: (Published 07 December 1996) Cite this as: BMJ 1996;313:1480
  1. T J Hendra,
  2. S P Gerrish,
  3. A R W Forrest
  1. Consultant physician Consultant anaesthetist Consultant chemical pathologist Royal Hallamshire Hospital, Sheffield S10 2JF

    EDITOR,—We agree with Emyr W Benbow and colleagues' suggestion that tissue redistribution may partly explain the postmortem increase in blood methadone concentration seen in our patient. In another recent case one of us (ARWF) found that a postmortem blood sample contained 71 μg methadone/l, whereas a sample obtained shortly before death contained 38 μg/l. One potential mechanism for the possible increase in …

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